GHK-Cu
Price range: $30.80 through $44.00
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Third-Party Lab Results
Transparency is our priority. Download the full HPLC and Mass Spectrometry reports for the current batch #88291. Tested on Oct 24, 2023.
DOWNLOAD FULL REPORT (PDF)GHK-Cu Certificate of Analysis
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Description
GHK-Cu (glycyl-L-histidyl-L-lysine–copper) is a naturally occurring copper-binding tripeptide found in human plasma, saliva, and urine. In experimental systems, GHK-Cu is widely used to investigate wound-repair mechanisms, extracellular matrix dynamics, angiogenesis, and antioxidant responses.
Preclinical and in vitro work suggests that GHK-Cu can modulate collagen and glycosaminoglycan turnover, influence fibroblast and immune-cell behavior, and interact with pathways related to oxidative stress and tissue injury signaling. GHK-Cu from research suppliers is intended strictly for laboratory use only and is not approved for human or veterinary consumption, cosmetic use, or any therapeutic application.
GHK-Cu is formed when the endogenous tripeptide GHK chelates copper(II) ions. Because of its presence in blood and tissue fluids, it is considered a physiologic carrier of copper, with roles in signaling and tissue maintenance that remain under active investigation.
In controlled research environments, GHK-Cu is commonly used to study:
- Skin and connective-tissue repair processes
- Fibroblast recruitment, proliferation, and matrix production
- Angiogenesis and endothelial-cell behavior
- Antimicrobial activity in wound models (when combined with selected co-factors)
- Neurobiological and gene-expression changes in nervous system models
- Experimental modulation of inflammatory and fibrotic responses
These applications make GHK-Cu a versatile tool for probing how small copper-peptide complexes participate in tissue-regeneration and stress-response pathways.
All peptides are supplied as sterile, lyophilized powder and are stable when handled correctly.
- On arrival: Store vials in a cool, dry place away from heat and direct sunlight.
- Long-term (powder): For optimal longevity, keep lyophilized peptides refrigerated to help maintain integrity.
- After reconstitution: Use an appropriate research diluent (for example, BAC water). Store the reconstituted solution in the refrigerator and use within 20–30 days for best stability.
Note: Minimize exposure to moisture and repeated freeze–thaw cycles. Follow your institution's safety procedures when handling research materials.
Q1: What is GHK-Cu in a research context?
A1: GHK-Cu is a naturally occurring copper tripeptide found in human plasma and other body fluids, used in laboratory research to study wound healing, extracellular matrix dynamics, angiogenesis, antioxidant responses, and gene-expression changes.
Q2: Why is GHK-Cu associated with skin and wound-healing research?
A2: In cell and animal models, GHK-Cu has been shown to influence collagen and matrix turnover, recruit fibroblasts and endothelial cells, and support revascularization, making it a key tool for investigating skin repair and tissue-regeneration pathways.
Q3: Does GHK-Cu have antimicrobial properties?
A3: GHK-Cu itself and particularly GHK-Cu combined with certain fatty acids have demonstrated antimicrobial activity in experimental settings, providing a basis for research into infection control and wound-healing complications.
Q4: Is GHK-Cu intended for cosmetic or therapeutic use?
A4: No. GHK-Cu supplied by research-focused vendors is for laboratory use only. It is not approved or intended for cosmetic application, human or veterinary consumption, or any diagnostic or therapeutic purpose.
Q5: In what other systems is GHK-Cu being studied?
A5: Beyond skin and wounds, GHK-Cu is being explored in nervous system, pulmonary, inflammatory, and pain models, including investigations into gene-expression modulation, neuroprotection, lung fibrosis, ARDS, and experimental analgesia.
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