Thymosin Alpha-1
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TB-500

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Price range: $33.60 through $48.00

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SCIENTIFIC SPECIFICATIONS
Molecular Formula
C212H350N56O78S
CAS Number
77591-33-4
Molar Mass
4963.4 g/mol
Amino Acid Sequence
Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser
Synonyms
Thymosin Beta-4, Tβ4, TMSB4X, PTMB4, TB500
Solubility
Water-soluble
Organoleptic Profile
White to off-white powder
Composition
Lyophilized powder – requires reconstitution
Research Use Only
● VERIFIED ANALYSIS

Third-Party Lab Results

Transparency is our priority. Download the full HPLC and Mass Spectrometry reports for the current Batch / Lot Number: TB414. Tested on April 30, 2026.

DOWNLOAD FULL REPORT (PDF)
PDF
COA 4126_TB
Verified by Biovirdian
Research Overview

TB-500 (Thymosin Beta-4) is a synthetic research peptide that mirrors a 43-amino-acid sequence of the naturally occurring actin-sequestering protein found in many tissues. It plays a significant role in cellular motility, tissue repair, and regeneration by modulating the polymerization and organization of actin filaments.

In preclinical models, TB-500 has been studied for its ability to influence cell migration, angiogenesis, and inflammatory responses. By regulating the G-actin/F-actin balance and promoting the expression of critical growth factors, TB-500 is a key tool in regenerative peptide research.

  • Alias: Thymosin Beta-4 (Tβ4)
  • Sequence: SDKP… (43 amino acids)
  • Molecular Formula: C212H350N56O78S
  • Molecular Weight: ~4963.5 Da
  • Purity: ≥98% (HPLC verified)
  • Form: Lyophilized peptide
  • For Research Use Only: Not for human or veterinary use
Storage & Handling

All peptides are supplied as sterile, lyophilized powder and are stable when handled correctly.

  • On arrival: Store vials in a cool, dry place away from heat and direct sunlight.
  • Long-term (powder): For optimal longevity, keep lyophilized peptides refrigerated to help maintain integrity.
  • After reconstitution: Use an appropriate research diluent (for example, BAC water). Store the reconstituted solution in the refrigerator and use within 20–30 days for best stability.

Note: Minimize exposure to moisture and repeated freeze–thaw cycles. Follow your institution's safety procedures when handling research materials.

FAQ 

Q: What is TB-500 derived from?
A: TB-500 is a synthetic peptide modeled after the natural protein Thymosin Beta-4, found in various mammalian tissues.

Q: What is the primary function of TB-500 in research?
A: It is used to study cellular migration, angiogenesis, and wound healing through actin cytoskeleton regulation.

Q: Is TB-500 injectable?
A: While some experimental studies use injection as a delivery method in animal models, TB-500 is strictly for research purposes and not for human administration.

Q: Can TB-500 promote muscle or tendon repair?
A: In preclinical studies, TB-500 has shown potential for improving soft tissue recovery in musculoskeletal models.

Q: Does TB-500 affect inflammation?
A: Yes. It has been studied for its anti-inflammatory and oxidative stress modulating properties, making it useful in systemic recovery models.

 

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Research Use Only: This product is intended for laboratory research use only and is not for human consumption, diagnostic, or therapeutic use.