Ipamorelin
Price range: $26.40 through $39.60
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Third-Party Lab Results
Transparency is our priority. Download the full HPLC and Mass Spectrometry reports for the current batch #88291. Tested on Oct 24, 2023.
DOWNLOAD FULL REPORT (PDF)Ipamorelin is a highly selective pentapeptide growth hormone secretagogue that activates the GHSR-1a (ghrelin receptor) without significantly influencing other pituitary hormones. This selectivity makes it ideal for modeling growth hormone (GH) release mechanisms while avoiding off-target effects such as ACTH, prolactin, FSH, LH, TSH, or cortisol modulation.
Ipamorelin triggers Gq/PLC-mediated calcium signaling, leading to GH release from somatotrophs in pituitary tissue. Its receptor-specific action and clean hormonal profile make it a valuable compound for laboratory research into peptide-driven endocrine signaling, metabolic regulation, and musculoskeletal repair models.
- Peptide Type: GH secretagogue analog
- Receptor Target: GHSR-1a (Ghrelin receptor)
- Sequence: Synthetic pentapeptide
- Signaling Pathways: Gq/PLC → Ca²⁺ release; cAMP
- Key Feature: Minimal impact on ACTH, prolactin, cortisol, or gonadotropins
- Use: For in-vitro and in-vivo preclinical research only
All peptides are supplied as sterile, lyophilized powder and are stable when handled correctly.
- On arrival: Store vials in a cool, dry place away from heat and direct sunlight.
- Long-term (powder): For optimal longevity, keep lyophilized peptides refrigerated to help maintain integrity.
- After reconstitution: Use an appropriate research diluent (for example, BAC water). Store the reconstituted solution in the refrigerator and use within 20–30 days for best stability.
Note: Minimize exposure to moisture and repeated freeze–thaw cycles. Follow your institution's safety procedures when handling research materials.
Q: What is the mechanism of action of Ipamorelin?
A: Ipamorelin binds the GHSR-1a receptor and activates intracellular calcium signaling via the Gq/PLC pathway, leading to growth hormone release.
Q: Does Ipamorelin affect cortisol or prolactin levels?
A: No. Unlike some other GH secretagogues, ipamorelin shows minimal activity on ACTH, cortisol, prolactin, or other pituitary hormones.
Q: What is the main advantage of using Ipamorelin in research?
A: Its high selectivity for GH release allows targeted investigation of GH-related signaling without cross-activation of the adrenal or gonadal axes.
Q: Is Ipamorelin intended for human use?
A: No. Ipamorelin is supplied strictly for laboratory use and not approved for human administration or clinical application.
Q: What type of studies commonly use Ipamorelin?
A: Preclinical studies in endocrinology, receptor pharmacology, tissue regeneration, and metabolic signaling frequently include ipamorelin as a reference compound.
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