Triptorelin (GnRH) 2 mg
Original price was: $44.00.$35.20Current price is: $35.20.
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Third-Party Lab Results
Transparency is our priority. Download the full HPLC and Mass Spectrometry reports for the current batch #88291. Tested on Oct 24, 2023.
DOWNLOAD FULL REPORT (PDF)Triptorelin is a synthetic decapeptide research compound and a structural analogue of endogenous gonadotropin-releasing hormone (GnRH), with the sequence pGlu–His–Trp–Ser–Tyr–D-Trp–Leu–Arg–Pro–Gly–NH₂. The substitution of D-tryptophan confers altered receptor interaction characteristics, making Triptorelin a valuable molecular tool for studying GnRH receptor pharmacology in controlled experimental systems.
In laboratory research models, Triptorelin binds to the GnRH receptor (GnRHR) expressed on pituitary-derived cells, activating Gq/11-coupled phospholipase C (PLC) signaling. This leads to IP₃-mediated intracellular Ca²⁺ mobilization and downstream signaling events that are central to investigations of hypothalamic–pituitary–gonadal (HPG) axis regulation, peptide–receptor kinetics, and endocrine feedback mechanisms.
Triptorelin is supplied exclusively for scientific and laboratory research use. It is not intended for human or veterinary consumption, clinical investigation, diagnostic use, or therapeutic application.
Chemical Identity & Classification
- Synthetic GnRH analogue (decapeptide)
- Neuropeptide hormone research compound
- GnRH receptor (GnRHR) agonist
Why Researchers Study Triptorelin
- To investigate GnRH receptor binding affinity and signaling dynamics
- To study structure–function relationships among GnRH analogues
- To explore regulatory mechanisms within the HPG axis in experimental models
Key Research Systems & Pathways
- GnRH receptor–mediated Gq/PLC signaling
- IP₃/DAG pathways and intracellular Ca²⁺ release
- Gonadotroph cell signaling networks
- Neuroendocrine feedback regulation mechanisms
Triptorelin is synthesized under controlled laboratory conditions to ensure high purity, molecular fidelity, and reproducibility for preclinical research applications.
All peptides are supplied as sterile, lyophilized powder and are stable when handled correctly.
- On arrival: Store vials in a cool, dry place away from heat and direct sunlight.
- Long-term (powder): For optimal longevity, keep lyophilized peptides refrigerated to help maintain integrity.
- After reconstitution: Use an appropriate research diluent (for example, BAC water). Store the reconstituted solution in the refrigerator and use within 20–30 days for best stability.
Note: Minimize exposure to moisture and repeated freeze–thaw cycles. Follow your institution's safety procedures when handling research materials.
What is Triptorelin used for in research?
Triptorelin is used in laboratory research to study GnRH receptor signaling, HPG axis regulation, and endocrine feedback mechanisms.
How does Triptorelin differ from native GnRH?
Triptorelin contains a D-tryptophan substitution that alters receptor interaction and signaling properties in experimental systems.
Which pathways are commonly studied with Triptorelin?
Research focuses on GnRHR-mediated Gq/PLC signaling and IP₃-driven intracellular Ca²⁺ pathways.
Is Triptorelin approved for human or clinical use?
No. Triptorelin is strictly for research use only and is not intended for human consumption, veterinary use, or clinical application.
How should Triptorelin be stored and handled?
Triptorelin should be stored and handled according to standard laboratory peptide storage and handling practices to maintain stability and integrity.
Researcher Reviews
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