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Snap-8

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Original price was: $33.00.Current price is: $26.40.

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SCIENTIFIC SPECIFICATIONS
Molecular Formula
C₄₁H₇₀N₁₆O₆S
CAS
868844-74-0
Molar Mass
1075.16 g/mol
Amino Acid Sequence
Cyclic peptide (no standard linear amino acid sequence)
Synonyms
Cyclopeptide derivative
Solubility
Water soluble
Form
Lyophilized powder
Research Use Only
● VERIFIED ANALYSIS

Third-Party Lab Results

Transparency is our priority. Download the full HPLC and Mass Spectrometry reports for the current batch #88291. Tested on Oct 24, 2023.

DOWNLOAD FULL REPORT (PDF)
PDF
HPLC_BPC157_Batch88291.pdf
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PDF
MS_BPC157_Batch88291.pdf
Verified by Janoshik
Description

SNAP-8 is a synthetic octapeptide research compound with the sequence Ac–Glu–Glu–Met–Gln–Arg–Arg–Ala–Asp–NH₂, structurally derived from SNAP-25, a core component of the SNARE protein complex involved in vesicle exocytosis. In laboratory research settings, SNAP-8 is studied for its ability to modulate vesicle fusion and neurotransmitter release mechanisms through competitive interaction with SNARE complex assembly.

Experimental studies utilize SNAP-8 as a molecular tool to investigate how interference with SNAP-25–dependent protein–protein interactions influences regulated exocytosis. By competing with endogenous SNAP-25 for SNARE complex formation, SNAP-8 provides a controlled model for examining catecholamine release regulation, vesicular trafficking, and cell–membrane interaction dynamics in non-clinical systems.

SNAP-8 is supplied exclusively for scientific and laboratory research use. It is not intended for human or veterinary consumption, clinical investigation, diagnostic use, or therapeutic application.

Overview

Chemical Identity & Classification

  • Synthetic octapeptide
  • SNAP-25–derived research peptide
  • Vesicular trafficking and exocytosis signaling compound

Why Researchers Study SNAP-8

  • To investigate SNARE complex assembly and regulation
  • To study vesicle fusion and neurotransmitter release mechanisms
  • To explore peptide-mediated modulation of cell–membrane interactions

Key Research Systems & Pathways

  • SNARE complex formation (SNAP-25–associated pathways)
  • Vesicular exocytosis and membrane fusion signaling
  • Catecholamine and neurotransmitter release models
  • Protein–protein interaction dynamics at cellular membranes

SNAP-8 is synthesized under controlled laboratory conditions to ensure high purity, molecular accuracy, and reproducibility for preclinical research applications.

Research

Mechanism of Action & Pathways

In experimental models, SNAP-8 is studied for its ability to compete with endogenous SNAP-25 during SNARE complex assembly. This competition alters vesicle docking and fusion efficiency, allowing researchers to analyze regulated exocytosis, membrane fusion kinetics, and downstream signaling effects associated with vesicular release processes.

 

Cellular & Molecular Research

SNAP-8 is commonly utilized in laboratory studies examining:

  • SNARE protein–protein interaction dynamics
  • Vesicle docking and membrane fusion assays
  • Modulation of catecholamine and neurotransmitter release
    All investigations are conducted in controlled in vitro or biochemical assay environments.

 

Neurobiology & Membrane Interaction Research

Research applications may include:

  • Neuronal and neuroendocrine cell signaling models
  • Vesicular trafficking and secretion pathway studies
  • Cell–membrane interaction and peptide localization analysis
    These investigations remain exploratory and mechanistic, without therapeutic interpretation.

 

Experimental Models

  • In vitro vesicle fusion and secretion assays
  • Ex vivo neural or secretory tissue studies
  • Non-clinical in vivo preclinical research models

All use is strictly limited to laboratory research contexts.

FAQ

What is SNAP-8 used for in research?
SNAP-8 is used in laboratory research to study SNARE complex assembly, vesicle exocytosis, and regulation of neurotransmitter and catecholamine release.

How does SNAP-8 interact with the SNARE complex?
SNAP-8 competes with SNAP-25 for participation in SNARE complex formation, altering vesicle fusion dynamics in experimental systems.

Which biological processes are commonly studied with SNAP-8?
Research focuses on vesicular trafficking, membrane fusion, and regulated exocytosis signaling pathways.

Is SNAP-8 approved for human or clinical use?
No. SNAP-8 is strictly for research use only and is not intended for human consumption, veterinary use, or clinical application.

How should SNAP-8 be stored and handled?
SNAP-8 should be stored and handled according to standard laboratory peptide storage and handling practices to maintain stability and integrity.

i
Research Use Only: This product is intended for laboratory research use only and is not for human consumption, diagnostic, or therapeutic use.

Researcher Reviews