Ara-290 (10mg)
Original price was: $49.50.$39.60Current price is: $39.60.
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Third-Party Lab Results
Transparency is our priority. Download the full HPLC and Mass Spectrometry reports for the current batch #88291. Tested on Oct 24, 2023.
DOWNLOAD FULL REPORT (PDF)ARA-290 is a small peptide derived from the structure of erythropoietin (EPO) and designed to selectively engage tissue-protective signaling pathways without the hematopoietic effects typically associated with EPO. In research settings, ARA-290 is primarily investigated for its interaction with the so-called innate repair receptor (IRR) and tissue-protective receptor (TPR), where it has been shown in preclinical and early clinical studies to influence inflammatory signaling, vascular repair mechanisms, neuropathic pain pathways, and wound-healing processes.
Supplied strictly as a research compound, ARA-290 is intended for use in controlled laboratory experiments only. It is not approved for human or veterinary consumption, diagnosis, treatment, or prevention of any disease.
ARA-290 is a non-erythropoietic EPO analogue engineered to retain tissue-protective and anti-inflammatory properties while minimizing effects on red blood cell production and cardiovascular parameters. By targeting specific EPO-related receptor complexes (often referred to as IRR/TPR), ARA-290 is used to explore:
- Modulation of inflammatory cytokine release
- Protection and repair of vascular and endothelial cells
- Regulation of immune-cell activity and antigen presentation
- Neural repair mechanisms and small fiber nerve integrity
- Wound repair and tissue regeneration in ischemic or inflammatory environments
Preclinical and translational research has examined ARA-290 in models of vascular injury, islet transplantation, autoimmune conditions, neuropathic pain, and small fiber neuropathy, making it a versatile tool for studying tissue protection and immune modulation.
All peptides are supplied as sterile, lyophilized powder and are stable when handled correctly.
- On arrival: Store vials in a cool, dry place away from heat and direct sunlight.
- Long-term (powder): For optimal longevity, keep lyophilized peptides refrigerated to help maintain integrity.
- After reconstitution: Use an appropriate research diluent (for example, BAC water). Store the reconstituted solution in the refrigerator and use within 20–30 days for best stability.
Note: Minimize exposure to moisture and repeated freeze–thaw cycles. Follow your institution's safety procedures when handling research materials.
Q1: What is ARA-290 in a research context?
A1: ARA-290 is a non-erythropoietic peptide derived from erythropoietin, used in research to study tissue protection, immune modulation, vascular repair, and neuropathic pain mechanisms via the innate repair/tissue-protective receptor pathways.
Q2: What are the main experimental applications of ARA-290?
A2: Common research applications include models of vascular and endothelial repair, islet transplantation, autoimmune and inflammatory diseases, neuropathic pain, small fiber neuropathy, and wound healing in metabolic disease.
Q3: How does ARA-290 differ from full-length erythropoietin (EPO)?
A3: ARA-290 is designed to selectively activate tissue-protective receptor complexes without stimulating the hematopoietic and many cardiovascular effects associated with full-length EPO, making it more suitable for focused tissue-protection and immune-modulation research.
Q4: Is ARA-290 intended for human or veterinary use?
A4: No. ARA-290 from research suppliers is for laboratory use only and is not intended for human or veterinary consumption, diagnosis, treatment, or prevention of any condition.
Q5: Why is ARA-290 of interest in neuropathy research?
A5: ARA-290 has been studied for its effects on small nerve fiber integrity, inflammatory signaling, and TRPV1-related pain pathways, making it a valuable compound for investigating mechanisms underlying neuropathic pain and small fiber neuropathy in controlled studies.
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