Follistatin-344 1mg
Original price was: $138.00.$110.40Current price is: $110.40.
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Third-Party Lab Results
Transparency is our priority. Download the full HPLC and Mass Spectrometry reports for the current batch #88291. Tested on Oct 24, 2023.
DOWNLOAD FULL REPORT (PDF)Follistatin-344 is a full-length synthetic analogue of naturally occurring follistatin, a binding protein best known for its ability to sequester and neutralize members of the TGF-β superfamily, including myostatin, activins, and, indirectly, follicle-stimulating hormone (FSH) signaling pathways. In preclinical models, these interactions have been associated with increased skeletal muscle mass, altered fibrosis patterns, and modulation of certain inflammatory responses.
As a research-only compound, Follistatin-344 is used to investigate muscle growth regulation, tissue remodeling, metabolic signaling, and tumor biology in controlled experimental systems. It is not intended for human or veterinary consumption, diagnosis, treatment, or prevention of any disease.
Follistatin is a secreted glycoprotein that binds and neutralizes several TGF-β family ligands, particularly myostatin and activins. Follistatin-344 is a synthetic counterpart of one of the main human isoforms and can be processed in vivo into other follistatin variants.
In research contexts, Follistatin-344 is employed to study:
- Myostatin and activin signaling in skeletal muscle growth and differentiation
- Cross-talk with insulin and IGF-1–related pathways
- Fibrosis, scar formation, and tissue repair biology
- The balance between cell proliferation and metastatic potential in cancer models
- Liver protection, fibrotic progression, and organ regeneration
- Developmental biology, including eye, nervous system, and hair-follicle formation
Because it sits at a key intersection of growth, differentiation, and remodeling signals, follistatin is a versatile tool for dissecting complex biological networks involving TGF-β family ligands.
All peptides are supplied as sterile, lyophilized powder and are stable when handled correctly.
- On arrival: Store vials in a cool, dry place away from heat and direct sunlight.
- Long-term (powder): For optimal longevity, keep lyophilized peptides refrigerated to help maintain integrity.
- After reconstitution: Use an appropriate research diluent (for example, BAC water). Store the reconstituted solution in the refrigerator and use within 20–30 days for best stability.
Note: Minimize exposure to moisture and repeated freeze–thaw cycles. Follow your institution's safety procedures when handling research materials.
Q1: What is Follistatin-344 in a research context?
A1: Follistatin-344 is a full-length synthetic analogue of the naturally occurring follistatin protein, used in laboratory models to study myostatin/activin inhibition, muscle growth regulation, tissue remodeling, and TGF-β family signaling.
Q2: How does follistatin relate to muscle growth research?
A2: Follistatin binds and neutralizes myostatin and activins, which normally inhibit muscle growth. In animal models, this can lead to increased muscle mass and strength, making Follistatin-344 a key tool in skeletal muscle and myopathy research.
Q3: Why is follistatin studied in cancer models?
A3: Follistatin is involved in TGF-β and BMP signaling, which influence cell proliferation, invasion, and metastasis. Research has linked follistatin levels to tumor growth characteristics and metastatic behavior in several cancer types, especially breast cancer.
Q4: Does follistatin have roles beyond muscle and cancer research?
A4: Yes. Follistatin is also investigated in liver protection and fibrosis, developmental eye and nerve formation, hair growth studies, and pancreatic β-cell and diabetes models, reflecting its broad impact on growth and differentiation pathways.
Q5: Is Follistatin-344 intended for human or veterinary use?
A5: No. Follistatin-344 is for laboratory research use only and is not intended for human or veterinary consumption, diagnosis, treatment, or prevention of any disease or condition.
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